DOX (Doxorubicin), CP (Cyclophosphamide), PARP-1 (Poly (ADP-Ribose) Polymerase 1), Bcl-2 (B-Cell Lymphoma 2), AC (Anticancer Chemotherapy), IL-3 (Interleukin-3), NF-B (Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells), COX-2 (Cyclooxygenase-2), IL-3 (Interleukin-3), CYP (Cyclophosphamide), 5-FU (5-Fluorouracil), MTX (Methotrexate), SOD (Superoxide Dismutase), CAT (Catalase), GPx (Glutathione Peroxidase), GST (Glutathione S-Transferase), MDA (Malondialdehyde), ROS (Reactive Oxygen Species)
L-Carnitine is also used for the treatment of patients who do not produce enough Carnitine and has been studied for its positive activity on muscle tissue affected by chemotherapy
Consequently, there is extensive established stability and shelf life for NAC [23]Ellis AG, Ching MS, Shilson AD, Kong DCM, Garrett K
Future studies should therefore adopt multi-center, adequately powered designs with neurological endpoints as primary outcomes rather than secondary observations
The transcription factor Nuclear factor erythroid 2related factor 2 (Nrf2) is closely associated with iron-dependent cell death and is a member of the solute carrier family 7 member 11 (SLC7A11)
However, a 2021 study by Sun et al
