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A warm thank you to all co-authors and collaborators, Asger Bihlet, Yves Henrotin, Francois Rieger, Olivier Godeaux, MD, MPH, Helene Rovsin, Peter Alexandersen, Edith Min Chu Lou for their dedication throughout this demanding but essential process

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Whilst this study primarily focused on metformin-mediated effects in tumour cells, increasing evidence implicates a role for metformin in the modulation of immune cells, with metformin demonstrated to modulate macrophage polarisation (71) and the infiltration and function of T-cells (72, 73)

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The hero ingredient, glutathione, a master antioxidant, helps defend against oxidative stress while promoting a visibly radiant and smooth complexion

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