Oxidative Stress Biomarkers and When Glutathione May Be Clinically Relevant Glutathione's role as an intracellular antioxidant is biochemically sound, but supplementation doesn't directly measure whether your oxidative stress burden actually warrants intervention
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Sources: Weschawalit, S., Thongthip, S., Phutrakool, P., & Asawanonda, P
Crucial in preventing oxidative cell damage Reduced glutathione (GSH) has over 90% of the total glutathione pool in cells
Affecting individuals across all ages and severities of initial infection, it presents with multisystemic manifestations, including fatigue, cognitive dysfunction, dyspnea, and cardiovascular abnormalities [10,11,12,13,14,15,16,20,31]
Alternative markers such as cystatin C-based eGFR or enzymatic creatinine assays may provide more accurate assessment when clinical concern exists, as recommended in KDIGO guidelines
