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Tremblay N, Blec C, Coulombe J, Godin C

In the rare cases of total deafness, an artificial inner ear, known as a cochlear implant, will be fitted

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Cell treatment For experiments involving amino acid starvation, cells were rinsed twice with PBS and incubated for 60 min in amino acid-free DMEM (MBS6120661) supplemented with 10% dialysed FBS

Therefore, we hypothesize that deregulated homocysteine metabolism in homocystinuria with severe hyperhomocysteinemia will lead to the cyclization of homocysteine into homocysteine thiolactone, which may render LDL less susceptible to oxidation