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After a first line of senolytic drugs tests, several new treatments targeting specific proteins expressed selectively during senescence or based on new technical developments will pave the way of preclinical research

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Astrocytes with low GSH may become less protective over time, releasing more inflammatory mediators and failing to supply an adequate amount of GSH and GSH precursors to neighboring neurons and microglia (Kwon et al., 2019

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However, other studies have indicated that nutritional stress resulting from Gln deprivation may promote tumor development