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Andreoli SP, McAteer JA, Seifert SA, Kempson SA

doi: 10.1111/j.1526-4637.2009.00613.x PMCID: PMC2891387 NIHMSID: NIHMS209741 Fibromyalgia Symptoms Are Reduced by Low-Dose Naltrexone: A Pilot Study Jarred Younger, PhD and Sean Mackey, MD, PhD Clin Rheumatol

Signs of organ dysfunction: Unexplained fatigue, yellowing of the skin or eyes, dark urine, or significant changes in urination

Difficulty walking When it is severe, a B12 deficiency can affect balance

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HPLC and mass spectrometry are both referenced in their lab material