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More severe cases may require 23 treatments per week for 4 weeks, followed by a gradual reduction to weekly sessions, while milder cases typically need fewer treatments

less than 25% of collagen fibers of a diffuse structure with a loss of boundary between individual fibers (score 1)

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Upon nerve injury, SARM1 undergoes a conformational change that activates its NADase activity, leading to the rapid depletion of NAD + 232