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PubMed and Scopus databases were searched in April 2024 using the search terms: (never-smokers OR never smokers OR never smok* OR nive OR healthy) AND (e-cig* OR e-cigarette OR ENDS OR electronic cigarette*) AND (respir* OR lung) AND (cohort or observational or follow-up OR randomized controlled trial OR RCT)

This data indicates a continuous reduction in the global smoking prevalence over nearly three decades, reflecting the effectiveness of anti-smoking campaigns and policies implemented worldwide

CDC - E-cigarettes and Youth: What Parents Need to Know offers information about e-cigarettes parents and caregivers can use when talking with their children about vaping

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