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Naloxegol treatment at 2 h post morphine injection resulted in significantly increased fecal output and small intestinal motility in mice expressing AAV-DIO-shMOR-EGFP compared to that of AAV-DIO-EGFP-expressing control mice (Fig

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Validated questionnaires were used to assess pain, disability, and quality of life both at baseline and during a 2-month follow-up