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The results indicated that in mice on the diet supplemented with cholestyramine, which depletes bile acids, APAP toxicity was exacerbated, whereas those on a diet supplemented with cholic acid had a more rapid recovery from APAP

Toxins are often called endocrine disruptors, meaning they fundamentally disturb hormonal function upon exposure

The nuclear factor-B (NF-B) pathway plays a central role in amplifying cellular inflammatory responses (Lawrence 2009)

Moreover, ferroptosis can propagate through intercellular mechanisms involving the release of damage-associated molecular patterns (DAMPs), dysregulation of immune checkpoints, and exosome-mediated signaling, collectively driving microglial activation, T-cell infiltration, and bloodbrain barrier disruption, culminating in systemic immune imbalance

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Glutathione contains anti-inflammatory properties