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Eluent B = 100 mM NaOH+500 mM sodium acetate (NaOAc)

The mixed solution will provide a single 10 mL dose which must be diluted prior to intravenous administration [see Dosage and Administration (2.3)]

The three phases are activation in weeks 14, remodeling in weeks 58, and maintenance in weeks 912

2009;60(Suppl 7):1916

Timeframe Considerations: The company notes that consistent use over several weeks is typical before users may notice changes, if any occur

Safety, Handling & Reconstitution For optimal solubility and structural stability, researchers must reconstitute the lyophilised solid using Bacteriostatic Reconstitution Solution (0.9% Benzyl Alcohol)