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In db/db mice, previous studies found that AMPK activation could reduce ROS production and increase mitochondrial biogenesis and ETC activity to alleviate kidney damage in diabetic models[150, 151]

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Gene expression analysis revealed that SH modulates the expression of genes involved in -1,3-glucan synthesis and transport, including upregulation of ZAP1 , ADH5 , XOG1 , and FKS1 , suggesting its potential mechanism involves enhancing cell wall-targeted antifungal responses (Shao et al., 2017

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