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While the ligands identified here are diverse, they represent many chemistries commonly encountered in plants, with the selectivity in recognition shown in just At GSTF2 and At GSTU19 demonstrating how these compounds could perform multiple and species-specific roles relating to signaling, transport and storage roles in both primary (fatty acid) and secondary (phenolic, alkaloid, and glucosinolate) metabolism, as has been recently proposed ( Statements Author contributions DD and RE conceived the experiments, interpreted the data and wrote the manuscript