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Human evidence remains confined to topical cosmetic work, including a 12-week trial in 71 women using formulations in the 0.11% concentration range applied to skin [5]

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Neuropharmacology 58(3):624631 Gourgiotis I, Kampouri NG, Koulouri V, Lempesis IG, Prasinou MD, Georgiadou G, Pitsikas N (2012) Nitric oxide modulates apomorphine-induced recognition memory deficits in rats