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How NSAIDs May Increase Free Radical Production NSAIDs work by inhibiting cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, which play a role in inflammation and pain signaling

Some chelators, such as D-penicillamine, also cause direct neurotoxicity, likely by crossing the blood-brain barrier and disrupting copper-dependent central nervous system enzymes, impairing energy metabolism, and increasing oxidative stress [245, 246]

-CO-NH- or reduced peptide bonds (CH 2 -NH 2 )

Effect of statin on age-related hearing loss via drug repurposing

In this context, the interaction between polyphenols and probiotics plays a significant role, with the potential to prevent and treat inflammation associated with changes in the intestinal microbiota, positively influencing the gutbrain axis

Moreover, we noticed that GSH and Glu induced distinct [Ca 2+ ] cyt transmission patterns in systemic leaves