Gomisin J was shown to suppress proliferation and induce necroptosis in the breast cancer cell lines MCF7 and MDA-MB-231, particularly in apoptosis-resistant cancers, making it a potential therapeutic for hard-to-treat malignancies [83]
We explore new methods that enhance the protective role of mucus through physical reinforcement, pathogen neutralization, muco-trapping and rehydration, as well as strategies that overcome the mucus barrier to improve drug delivery, including physical modulation, mucoadhesive design, muco-penetrating design, mucolytics and active targeting
Crider, K
A comprehensive review of conventional and stimuli-responsive delivery systems for bioactive peptides: from food to biomedical applications
Crystallization during freezing and thawing can damage the peptide structure
Patrushev, N., Seidel-Rogol, B