10.1074/JBC.M710012200 50 DhakshinamoorthyS.JainA
Am J Respir Crit Care Med 162 : 23412351 Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CP, Gustafsson P, Jensen R, Johnson DC, MacIntyre N, McKay R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J 2005 Standardisation of spirometry
Pohl et al., 2011
In the context of heart failure, clinical evidence demonstrates that CoQ10 supplementation is associated with significant improvements in New York Heart Association functional classification, as well as a reduction in major adverse cardiovascular events [21]
However, these hypotheses remain to be tested
Important things to consider for the rate of administration include: Watching the patients vital signs Changing the rate based on how the patient reacts Not giving it too fast to prevent bad reactions Emergency Protocols for Severe Deficiency For severe Vitamin B12 deficiency with neurological symptoms or severe anemia, emergency steps are needed
