Takayama K, Ito K, Matsui A, Yamashita T, Kawakami K, Hirayama D et al (2021) In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
In a cross-sectional study with 125 women with PCOS, elevated serum selenium and SELENOP were shown to have higher total antioxidant capacity and GPx activity (selenium-dependent antioxidant enzyme) as well as lower markers of lipid peroxidation
Role of gut microbiota in hepatocarcinogenesis
The PNPLA3 I148M polymorphism is more frequently present in the Hispanic population, less in those of European descent, and lowest in African-American populations (Romeo et al., 2008)
Therefore, considering that there is a lot of evidence about the role of senescence on insulin resistance and inflammation as the main problems in obesity and related disorders and even resistance to weight loss, it seems that reduce or prevent senescence can be used as a therapeutic solution in the treatment of obesity and its complications
doi: 10.1073/pnas.2101718118 43 CircuM