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About the Study New research findings published in Nature Medicine come from an analysis of the large-scale COSMOS (COcoa Supplement and Multivitamin Outcomes Study) clinical trial

Fremont R, Tewari A, Angueyra C, Khodakhah K

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"Energy metabolism in migraine patients: a 31P-MRS study." Brain , 124(11), 2229-2236

In comparison, patients who used retatrutide (8 mg and 12 mg once weekly) lost 17.5% at 24 weeks and 24.2% of their body weight after 48 weeks in phase 2 clinical trials