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Bradstreet, et al

Vitamin C can counteract the consequences of long-term alterations that can generate free radicals, even though these effects have been shown to inhibit the production of antioxidant defense, lower proteolytic activity, and encourage the buildup of oxidized proteins (78, 79)

Cold Spring Harb Perspect Med 1, a009316 (2011)

Further evaluation revealed chronic therapeutic use of paracetamol and elevated urinary 5-oxoproline levels, which confirmed pyroglutamic acidosis

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