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According to Xiao et al., tanshinone I could effectively induce cell ferroptosis (88)

Furthermore, aflatoxins, especially aflatoxin B1 (AFB1) produced by Aspergillus species, induce DNA damage and mutations (e.g., in TP53), vastly increasing HCC risk, particularly in the context of HBV coinfection 141,142,143

doi: 10.1093/aje/kww120 177 GianFrancescoMAStridhPRheadBShaoXXuEGravesJSet al

Finco D, Baltrukonis D, Clements-Egan A, Delaria K, Gunn GR 3rd, Lowe J, et al

VetOne is a registered trademark of MWI Animal Health

The third family, IGF-1 LR3, skips the GH-signaling step entirely, binding directly to the IGF-1 receptor on muscle tissue and activating the PI3K/Akt and MAPK pathways tied to cell growth