10.1016/j.biomaterials.2021.121110 52 PearsonS
Understanding how this compound compares to other dominant peptides in the anti-aging research space Epithalon and MOTS-C helps clarify where each tool fits
In some embodiments, the auris-acceptable penetration enhancer is a surfactant comprising an alkyl-glycoside wherein the alkyl glycoside is maltose, sucrose, glucose, or a combination thereof linked by a glycosidic linkage to an alkyl chain of 9-16 carbon atoms (e.g., nonyl-, decyl-, dodecyl- and tetradecyl sucroside
The mechanism is well-characterized
This technique estimated that the dielectric constant of myelin is increased by 10% in MS brain, which would translate into a global 10% reduction of conduction velocity in white matter axons (Teo et al., 2021)
The compounds don't compete for binding sites, don't share metabolic pathways during clearance, and don't modulate the same downstream signaling cascades