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Dougnon G, Matsui H (2025) Lipofuscin accumulation in aging and neurodegeneration: a potential timebomb overlooked in Alzheimers disease

Discussion Disorders in melanin formation have been linked to various skin diseases in humans such as hyperpigmentation and skin cancer

Sulfotransferases are also present in the intestine, brain and platelets of blood

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In this study, AMPK was verified to inhibit ferroptosis induced by IRI in diabetic hearts via inactivation of NADPH oxidase 2 (NOX2), suggesting that the inhibitory effect of AMPK/NOX2 on ferroptosis may be another important protective mechanism in infarcted hearts[148]