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Tirzepatide is studied as a dual agonistmeaning it activates both the GIP receptor (one incretin pathway) and the GLP-1 receptor (another incretin pathway)

Increased energy, better focus, improved mood, and more restful sleep are common signs

Volume, not dose

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Once anesthetized, the right knee joints of the animals were shaved, sterilized, and subjected to an intra-articular injection of collagenase type II