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In order to mirror chronic administration in clinical populations, the number of chronic dosage regimens in animal studies should also be enhanced

We found a significant lower SDF in patients on AOX compared to controls when the analysis was repeated after the exclusion of one study carried out in patients treated with varicocele repair and AOX or placebo/no treatment [29] (SMD -1.47 [95% CI: -2.18, -0.77]

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HLCs cultured in 24-well plates were treated with different concentrations of NH4Cl (0, 2 or 5 mM) in 1 ml Hepatocyte Maintenance Medium for 24 h

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Harada K, Hwang H, Wang X, Abdelhakeem A, Iwatsuki M, Blum Murphy MA, Maru DM, Weston B, Lee JH, Rogers JE, Thomas I, Shanbhag N, Zhao M, Bhutani MS, Nguyen QN, Swisher SG , Ikoma N, Badgwell BD, Hofstetter WL, Ajani JA