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Selenium, an antioxidant nutrient

doi: 10.3389/fphar.2017.00214 47 ChuCLLeeYPPangCYLinHRChenCSYouRI

Finally, B12 is required to make myelin, the protective layer that coats nerve cells. B12 also works alongside folate to produce red blood cells, and without adequate B12 those cells grow abnormally large and lose their ability to carry oxygen efficiently

79,80 This phenomenon has been seen in patients with chronic kidney disease (CKD), and a phase II CKD cohort study found that plasma Leu and valine are significantly decreased in CKD patients compared with normal controls

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Recognizing this potential for masking is the first critical step toward ensuring comprehensive and timely support