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Relevant randomized controlled trials (RCTs) were identified from Embase, MEDLINE, the Cochrane Library database, and ClinicalTrials.gov from inception to March 15, 2024

Ide V, Vanderschueren D, Antonio L

If fatigue continues, a clinician may evaluate anemia, thyroid disease, sleep problems, medication effects, mood concerns, or other causes

Nrf2 mediates the DNA methylation level of RANKL promoter by regulating the activity of DNA methyltransferase 3a, participating in the regulation of ferroptosis in osteoclasts and bone homeostasis

S., Ribeiro, A

Enhanced Metabolism and Weight Management- Vitamin B12 is essential for converting carbohydrates into glucose leading to energy production and a decrease in fatigue and lethargy