Because men with high levels of ROS have a seven-fold lower likelihood of inducing a pregnancy than men with lower levels, researchers recommend that treatment for infertile men should include strategies to reduce oxidative stress and improve sperm quality
Adv Exp Med Biol (2020) 1277:14358

N-Acetyl-L-Cysteine (NAC) by Designs for Health provides 900 mg per capsule of this powerful amino acid precursor to glutathione the body's master antioxidant.* It supports healthy liver function, optimal detoxification, antioxidant status, muscle recovery, lung health, and brain function.* N-Acetyl-L-Cysteine is formulated to support healthy liver function and normal detoxification by promoting glutathione production.* Glutathione is the body's primary antioxidant for neutralizing free radicals and clearing unwanted compounds.* Individual results may vary based on diet, lifestyle, and overall health status.* Key benefits include support for normal glutathione status, healthy liver function, optimal detoxification, antioxidant status, muscle function and recovery, and brain and lung health.* These benefits stem from NAC's role as the rate-limiting precursor to the body's glutathione production.* Take one capsule per day, or as directed by your healthcare practitioner
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Still, formal large-scale safety studies will be essential to solidify best practices
While supplementation can be beneficial, factors such as diet, sleep, lifestyle and overall health also play an important role in maintaining healthy glutathione levels