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If excess free copper were present in a poorly manufactured preparation, it could generate hydroxyl radicals via Fenton-type chemistry and produce artifactual oxidative stress in cell cultures

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6-AH family members were found to act as mimics of the dimerization domain of FIGF (hinge region), and inhibited the interaction of an HGF molecule with a 3 H-hinge region peptide resulting in an attenuated capacity of HGF to activate its receptor Met

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Brenner, R