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HD is induced by the expansion of CAG repeats in the Huntingtin (Htt) gene, resulting in the formation of mutant Huntingtin (mHtt) (Figure 4E

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We have emergency protocols in place though we've rarely needed them

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JIB-04, a pan-inhibitor of histone demethylases, targets histone-lysine-demethylase-dependent AKT pathway, leading to cell cycle arrest and inhibition of cancer stem-like cell properties in hepatocellular carcinoma cells