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serum is plasma with the clotting factors removed.) The more common plasma and serum tests measure extracellular (outside of cells) levels of nutrients, while RBC tests measure intracellular (inside of cells) levels of nutrients
Pregnancy and lactation Daily iodine requirements are significantly increased in pregnant and breastfeeding women because of (1) the increased thyroid hormone production and transfer to the embryo/fetus in early pregnancy before the fetal thyroid gland becomes functional, (2) iodine transfer to the fetus during late gestation, (3) increased urinary iodine excretion, and (4) iodine transfer to the infant via breast milk (see also The RDA) (14, 21)
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