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doi: 10.1016/j.biopha.2017.10.082 58

doi: 10.1172/JCI87800 59 KraftVBezjianCTPfeifferSRingelstetterLMullerCZandkarimiFet al

High concentrations of copper ions can activate autophagy through lysosome-dependent mechanisms [158]

Indeed, exosomes hold promise for non-invasive cancer diagnosis through the detection of their biochemical components, targeted drug delivery by leveraging their complete biocompatibility, and cancer immunotherapy by modulating the complex interplay with the immune system [92, 93]

5H, I), while overexpression of a codon-optimized L2HGDH (L2HGDH OPT ), which is resistant to the designed sgRNA, reverses this effect (Fig

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