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High doses of B12 may worsen the disease and cause irreversible damage to the optic nerve

This is believed to result from the increased blood volume induced by methylcobalamin

Common side effects of vitamin B12 injections include mild diarrhea, itching, nausea and vomiting, dizziness, headaches, and hot flashes

There are rare occasions where vitamin B12 causes allergic reactions or sensitivity

Now, while injectable B12 is generally very safe, it is important to be aware of potential side effects

For others, it might take a few weeks of consistent injections before you notice a change if your symptoms are more complicated, such as numbness, exhaustion, or memory problems