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Elsevier Ltd., Amsterdam, Netherlands, pp 123130

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Contrary to claudin-1, which in normal colonic epithelial cells is expressed to a minimum (even though it is highly increased in colon cancer tissue and cells 65 ), the claudin-7 protein is highly expressed in the colonic epithelium

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It is caused by an autoimmune reaction that destroys the stomach cells responsible for producing intrinsic factor

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