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The PDA (72 g/mL, 1 mL) and PDA@Pt (which contains 72 g/mL PDA, 100 g/mL, 1 mL) solutions were prepared and subjected to irradiation with an 808 nm laser (1.0 W/cm 2 , 10 min) with concurrent monitoring of temperature changes

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After complete dissolution of the gel, the sample was added to a Qiagen spin column which was then centrifuged at 9200 g for 1 min