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The serine de novo synthesis pathway (SSP) represents a pivotal metabolic bypass of glycolytic metabolism, whereby the glycolytic intermediate 3-phosphoglyceric acid is converted into serine and glycine through the action of numerous metabolic enzymes, including phosphoglycerate dehydrogenase (PHGDH)

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For these reasons, current guidelines recommend long-term PPI use when clinically indicated without the need for routine monitoring

Improved Stability: The phospholipid bilayer protects glutathione from degradation in the gastrointestinal tract

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Timing Baseline Marker Fasting glucose Why it matters Gives a current glucose snapshot, especially when appetite and diabetes medication needs change