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The most common B12 subcutaneous injection sites are the following: The upper arm To self-administer a B12 injection into the arm, pinch a thick skin layer of the side or back of the upper arm and insert the needle at a right angle
If the syringe fills with blood, remove the needle and start again at site a few centimetres further down your leg
Phase 2 trial data (Jastreboff et al., NEJM 2023) demonstrated average weight reductions of approximately 1724% over 48 weeks notably higher than currently approved GLP-1 receptor agonists such as semaglutide, though direct comparisons are limited by differences in trial populations and designs
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