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While GHSR1a activity in the hypothalamus is likely heavily involved in homeostatic mechanisms, its presence in extra hypothalamic regions, including a number of limbic and midbrain structures like the ventral tegmental area (VTA), suggest that this receptor is associated in processes associated with learning and motivation (Abizaid et al., 2006

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Akt activation is required at a late stage of insulin-induced GLUT4 translocation to the plasma membrane

Inflammaging: a new immunemetabolic viewpoint for age-related diseases