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While anyone can benefit from healthy B12 levels, certain groups are more likely to experience deficiencies and may see greater advantages from supplementation: Vegans and vegetarians: B12 is primarily found in animal products, making supplementation critical for those on plant-based diets

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BPC-157 doesnt appear to carry those risks

Osteoporosis High blood concentrations of homocysteine may affect bone remodeling by increasing bone resorption (breakdown), decreasing bone formation, and reducing bone blood flow

And some medical professionals even endorse them

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