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It is also widely available as a dietary supplement in several forms and is frequently promoted for fat burning, performance, recovery, heart health, and cognitive support

* I have been sitting on this review for over a year, alternately confused and disgusted and wondering and puzzled

The intracellular peripheral membrane proteins include the zonula occludens (ZO) family, ZO-1 (also known as tight junction protein-1 [TJP1]), ZO-2, and ZO-3 as well as cingulin, whilst the transmembrane proteins include occludin, tricellulin, and members of the claudin family

It has been identified as a key contributing factor in the initiation and progression of low-grade systemic inflammation [22]

W., Bracken, C

Gastroenterology 163 , 495506.e8 (2022)