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Among elderly patients belonging to the Framingham cohort, Lidenbaun [9] observed a prevalence of over 5.3%

It is important to check folate status alongside B12, but folate supplementation should not be started before excluding B12 deficiency, as this may precipitate neurological complications

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Peptide injections work with your bodynot against itand are safe for long-term use

None of these pathways directly substitute for another, which is part of why researchers interested in a fuller picture of metabolic regulation may look at all three within the same body of literature not to combine effects, but to understand how separate systems might interact at a mechanistic level