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Comai, S., Ochoa-Sanchez, R

Moreover, mitochondrial dysfunction and related oxidative stress can activate the innate branch of the immune system, leading to the release of pro-inflammatory cytokines influencing various depression-related pathophysiological mechanisms: monoaminergic neurotransmission disruption, tryptophan degradation toward neurotoxic catabolites, glutamate-related excitotoxicity, decreased neurotrophic factors and alterations in the hypothalamic-pituitary-adrenal axis [3, 33, 59]

Griendling KK, Sorescu D, Lassegue B, Ushio-Fukai M: Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology

doi: 10.3389/fimmu.2021.711650 17 LeeLYYIzzardLHurtAC

FAQ Basics What is the KLOW peptide, and what is in the KLOW blend / stack

When applied together: A daily ritual of renewal, this cream isnt just skincareits an intimate dialogue with the bodys memory of youth