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"We initially expected that serum from vapers would either exhibit the same harmful properties as serum from smokers, or would lack some harmful properties that smoker serum exhibits." Instead, rather than finding smoking to be the most dangerous activity, the team concluded that vaping and smoking in combination is the worst thing you can do

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Fatigue is one of the factors most commonly associated with migraines

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thus taking a closer look at other types of medication that are also being used can be a way of possibly pinning down the cause