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The potential role for drug modulation of these other neurotransmitters and receptor types is an active area of research and novel drug discovery for PD

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Thus, the results indicate that polymorphisms in TNFA (TNF-), TNFRSF1A (TNFR1) and TNFAIP3 (A20), which upregulate TNF- signaling, were associated with beneficial response to anti-TNF therapy among patients with IBD

Anal Biochem 72:248254