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A study evaluating the effectiveness of a 45-day VLEKT in improving acne in 31 young women with moderate acne and grade I obesity showed a reduction in markers of oxidative stress, such as reactive oxygen metabolite derivatives (dROMs), and a decrease in pro-inflammatory metabolites, including trimethylamine N-oxide (TMAO)
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Zhongguo Zhong Xi Yi Jie He Za Zhi 24(5):422426 Takahashi K et al (2008) Neuronal apoptosis and inflammatory responses in the central nervous system of a rabbit treated with Shiga toxin-2
While it is generally understood that efflux pumps often play an important role in drug-resistant phenotypes, it remains poorly defined how molecular structure drives recognition by efflux pumps