Cell culture studies have shown that NNMT inhibition increases intracellular NAD+ levels, enhances sirtuin activity, and shifts adipocyte metabolism toward greater fatty acid oxidation
The optimal dose sits at the intersection of tolerability and metabolic response which is rarely identical between patients
Consistent with these findings, caspase-3/7 activity showed a modest, non-significant increase with MitoQ alone after 24h, but was elevated when MitoQ was combined with DPI
All quantitative efficacy data (body-weight loss, fat-mass reduction) comes from a single diet-induced-obese mouse study
Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt-containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production, and regulation
Your suitability also depends on your general health and medical history