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The extant body of scholarly work indicates that these botanical supplements manifest their antidepressant properties not merely through straightforward pharmacodynamic mechanisms but rather via extensive modulation of neurochemical networks at a systemic level

It has been suggested that Mucuna pruriens contains more bioactive compounds than LDs and may have a neuroprotective effect against PD [26]

Sun Y, Wang X, Zhou Y, Zhang J, Cui W, Wang E, Du J, Wei B, Xu X (2021) Protective effect of metformin on BPA-induced liver toxicity in rats through upregulation of cystathionine synthase and cystathionine lyase expression

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J Clin Hypertens 21(8):10911098

Siegel RL, Kratzer TB, Giaquinto AN et al (2025) Cancer statistics, 2025