During fasting with decreased intra-portal insulin levels, hepatic GH sensitivity decreases leading to decreased serum IGF-I levels despite a compensatory increase in GH secretion
They produce enough in their digestive systems via bacterial fermentation
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View Source Endocrinology Synergistic effects of growth hormonereleasing peptide and growth hormonereleasing hormone 1990 DOI: 10.1210/endo-127-6-3093 PMID: 2123433 Bowers CY, Reynolds GA, Durham D, Barrera CM, Pezzoli SS, Thorner MO View Source The Journal of clinical endocrinology and metabolism Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults 2006 DOI: 10.1210/jc.2005-1536 PMID: 16352683 Teichman SL, Neale A, Lawrence B, et al
Ze wzgldu na stabilno w soku odkowym, BPC 157 moe by skuteczny rwnie przy podaniu doustnym, cho biodostpno jest nisza
doi: 10.1186/s12967-021-02724-6
