Jan 8: Astellas has failed to gain approval for what would be the first approved therapy targeting claudin 18.2 (CLDN18.2), a transmembrane protein expressed on the surface of gastric epithelial cancer cells
It is also a potent MAO inhibitor and carries an FDA boxed warning for serotonin syndrome when combined with SSRIs and similar drugs, a risk most clearly documented at intravenous and higher doses
TB-500 promotes angiogenesis (new blood vessel formation), which raises theoretical concerns for individuals with cancer history or risk factors
Ele poderia, sim, ter seguido caminhos mais rentveis e bvios e talvez hoje estivesse no topo do mundo mas escolheu, com rara integridade, o ofcio de criar para quem realmente o escuta, em vez de agradar a plateias inteiras de passagem
A 10 L sample was injected, with a total run time of 17 minutes
The word mycotoxin comes from the Greek mykes (fungus) and the Latin toxicum (poison)