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Morphew et al ., Reference Morphew, Wilkinson, Mackintosh, Jahndel, Paterson, McVeigh, Abbas Abidi, Saifullah, Raman, Ravikumar and LaCourse2016)

An independent DSMB will review the safety data periodically

Yamazaki, K

To investigate whether DAM and DAA are associated with neurodegeneration in GCLC-KO mice, we conducted qRT-PCR analyses of DAM and DAA-related genes using cortical samples from 4-month-old GCLC-KO and WT mice (Fig

The concentration of leukotriene D(4) (LTD(4)), which is usually not detectable, was highly increased, whereas LTE(4), the major urinary metabolite in humans, was completely absent

These results suggest that YBX1 is required for -KG to dictate AMPK translation